Free Rare Disease CME Courses

Diagnosing and managing rare diseases often requires a unique blend of clinical insight, awareness of emerging therapies, and a deep understanding of complex presentations. For healthcare professionals working in this specialized area, FreeCME.com offers a diverse library of free continuing medical education (CME) courses designed to support excellence in care for patients with rare and orphan conditions. These no-cost activities are developed to help physicians, nurse practitioners, physician assistants, and other clinicians stay current with the latest advancements in rare disease research, diagnostics, and treatments—while fulfilling important professional education requirements.

Covering a Wide Range of Rare and Orphan Conditions

FreeCME’s rare disease CME curriculum spans a broad spectrum of clinical areas, from genetic metabolic disorders to autoimmune syndromes, neurodegenerative conditions, and rare cancers. Learners can access courses on diseases such as spinal muscular atrophy (SMA), amyloidosis, Fabry disease, Gaucher disease, idiopathic pulmonary fibrosis (IPF), paroxysmal nocturnal hemoglobinuria (PNH), and many more.

Our offerings also explore the diagnostic journey often associated with rare diseases, including delays in recognition, misdiagnosis, and the psychosocial challenges patients face. Activities highlight the latest treatment strategies, clinical trial updates, and FDA-approved therapies—many of which represent groundbreaking advances in personalized or precision medicine.

Learn at Your Pace With Flexible Course Formats

Recognizing the time constraints of busy clinicians, FreeCME.com offers its rare disease CME content in a variety of accessible, user-friendly formats. Choose from on-demand video lectures, expert panel discussions, case-based interactive modules, and concise written activities. Courses are designed to fit into your workflow—whether you have time for a deep dive or just a quick refresher between patients.

All activities feature defined learning objectives, self-assessment tools, and downloadable certificates upon completion. Many are eligible for AMA PRA Category 1 Credit™, ANCC contact hours, or AAPA credits, ensuring that you can earn the CME you need in a format that works for your schedule.

Expert-Led Content Backed by Clinical Evidence

Rare disease CME activities available on FreeCME.com are developed in partnership with leading academic institutions, nonprofit organizations, and specialty-focused medical education providers. Each course is led by experienced clinicians and researchers who are actively involved in rare disease diagnosis, treatment, or drug development. These experts offer valuable real-world insights and up-to-date information on disease mechanisms, clinical manifestations, and evolving standards of care.

Courses are grounded in the latest evidence and often include references to recently published studies, newly approved therapies, and best-practice guidelines issued by expert panels and rare disease organizations.