This activity will offer opportunities to review symptoms and clinical manifestations of MPS I, and discuss practical approaches for screening and accurate disease diagnosis.

Demonstrate an enhanced index of suspicion for the diagnosis of a genetic mitochondrial disease in infants, children, and adults who present with progressive muscle weakness

Commentary on state-of-the-art management and prevention of coronary artery disease (CAD) and peripheral arterial disease (PAD), with antithrombotic strategies

Describe the epidemiology and mechanisms of drug-resistance among Gram-negative (GNB) and Gram-positive (GPB) bacterial infections

In these articles, 2 expert faculty members discuss how busy PCPs can optimize MDD care by implementing shared decision making; employing measurement-based care; identifying and managing MDD residual symptoms and antidepressant side effects; and switching patients to new antidepressants when necessary. Two patient cases illustrate evidence-based approaches to common clinical scenarios.

This activity is designed for all healthcare team members who may encounter Familial Hypercholesterolemia in practice.

Discuss the latest evidence regarding the pathophysiology of severe asthma

A concise and focused overview of the pathophysiology of α1-antitrypsin deficiency (AATD), the clinical presentation and diagnostic evaluation of patients with this condition, and the efficacy and safety of therapies recommended for the management of pulmonary complications.