Recognizing and Managing HoFH: Clinical Cases
Released On
November 5, 2024
Expires On
November 5, 2025
Media Type
Internet
Completion Time
60 minutes
Specialty
Cardiology, Endocrinology, Genetics, Primary Care
Topic(s)
Cardiovascular Disease, Heart Disease
This activity is jointly provided by Global Education Group and PlatformQ Health Education, LLC, in collaboration with the American Society for Preventive Cardiology (ASPC)
This activity has been supported by an independent educational grant from Regeneron Pharmaceuticals, Inc.
Credit Available
- Physicians — maximum of 1.0 AMA PRA Category 1 Credit(s)™
All other healthcare professionals completing this course will be issued a statement of participation.
Target Audience
The target audience for this activity are cardiologists, endocrinologists, PCPs, and internal medicine physicians.
Program Overview
Advances in the understanding of homozygous familial hypercholesterolemia (HoFH) have led to the development of new treatment options. As clinical data continues to emerge, clinicians must be aware of how to integrate these new therapies into their practice so they can improve the diagnosis and treatment of the disorder to reduce the associated clinical and public-health burden. In part two of an overall three-part educational series, lipid experts will discuss how clinicians can improve awareness, screening, and diagnosis of HoFH to reduce delays in treatment initiation. The education will also focus on improving communication between clinicians and patients with HoFH and their families.
Learning Objectives
After completing this activity, the participant should be better able to:
- Distinguish suggested screening approaches and diagnostic criteria for HoFH
- Review strategies for incorporating therapies for HoFH into a patient-centered management plan
- Discuss the mechanisms of action and efficacy and safety data for newer agents for HoFH, including emerging indications
Faculty
James A. Underberg, MD, MS, FACP, MNLA
Clinical Assistant Professor of Medicine
NYU Grossman School of Medicine
Deepak L. Bhatt, MD, MPH, MBA, FACC, FAHA, FESC, MSCAI
Director of Mount Sinai Fuster Heart Hospital
NDr. Valentin Fuster Professor of Cardiovascular Medicine
Icahn School of Medicine at Mount Sinai
Accreditation Statement
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Global Education Group (Global) and PlatformQ Health Education, LLC. Global is accredited by the ACCME to provide continuing medical education for physicians.
Credit Designation
Global Education Group designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Disclosures of Relevant Financial Relationships
Global Education Group (Global) adheres to the policies and guidelines, including the Standards for Integrity and Independence in Accredited CE, set forth to providers by the Accreditation Council for Continuing Medical Education (ACCME) and all other professional organizations, as applicable, stating those activities where continuing education credits are awarded must be balanced, independent, objective, and scientifically rigorous. All persons in a position to control the content of an accredited continuing education program provided by Global are required to disclose all financial relationships with any ineligible company within the past 24 months to Global. All financial relationships reported are identified as relevant and mitigated by Global in accordance with the Standards for Integrity and Independence in Accredited CE in advance of delivery of the activity to learners. The content of this activity was vetted by Global to assure objectivity and that the activity is free of commercial bias.
All relevant financial relationships have been mitigated.
The faculty have the following relevant financial relationships with ineligible companies:
- James A. Underberg, MD, MS, FACP, MNLA
- Consulting Fee (e.g., Advisory Board): Ionis Pharma, Esperion Pharma, Amgen Pharma, New Amsterdam Pharma
- Contracted Research (Principal Investigators must provide information, even if received by the institution): Chiesi Pharma
- Speakers' Bureau: Esperion, Amgen, Regeneron
- Stock Shareholder (Individual stocks/Stock options; diversified mutual funds do not need to be disclosed): New Amsterdam, Precision Biosciences, Verve Therapeutics
- Deepak L. Bhatt, MD, MPH, MBA, FACC, FAHA, FESC, MSCAI
- Consulting Fee (e.g., Advisory Board): Angiowave, Bayer, Boehringer Ingelheim, CellProthera, Cereno Scientific, Elsevier Practice Update Cardiology, Janssen, Merck, MyoKardia, NirvaMed, Novo Nordisk, PhaseBio, PLx Pharma, Stasys, GlaxoSmithKline, Hims, SFJ, Youngene
- Contracted Research (Principal Investigators must provide information, even if received by the institution): Abbott, Acesion Pharma, Afimmune, Aker Biomarine, Alnylam, Amarin, Amgen, AstraZeneca, Bayer, Beren, Boehringer Ingelheim, Boston Scientific, Bristol-Myers Squibb, Cardax, CellProthera, Cereno Scientific, Chiesi, CinCor, Cleerly, CSL Behring, Eisai, Ethicon, Faraday Pharmaceuticals, Ferring Pharmaceuticals, Forest Laboratories, Fractyl, Garmin, HLS Therapeutics, Idorsia, Ironwood, Ischemix, Janssen, Javelin, Lexicon, Lilly, Medtronic, Merck, Moderna, MyoKardia, NirvaMed, Novartis, Novo Nordisk, Otsuka, Owkin, Pfizer, PhaseBio, PLx Pharma, Recardio, Regeneron, Roche, Sanofi, Stasys, Synaptic, The Medicines Company, Youngene, 89Bio
- Honoraria: CSL Behring
- Stock Shareholder (Individual stocks/Stock options; diversified mutual funds do not need to be disclosed): Bristol Myers Squibb
- Stock Option Holder (Individual stocks/Stock options; diversified mutual funds do not need to be disclosed): Angiowave
- Other (Describe): Data Monitoring Committees: Acesion Pharma, Assistance Publique-Hôpitaux de Paris, Baim Institute for Clinical Research (formerly Harvard Clinical Research Institute, for the PORTICO trial, funded by St. Jude Medical, now Abbott), Boston Scientific (Chair, PEITHO trial), Contego Medical (Chair, PERFORMANCE 2), Mount Sinai School of Medicine (for the ENVISAGE trial, funded by Daiichi Sankyo; for the ABILITY-DM trial, funded by Concept Medical; for ALLAY-HF, funded by Alleviant Medical), Novartis
- Site Co-Investigator: Abbott, Biotronik, Boston Scientific, CSI, Endotronix, St. Jude Medical (now Abbott), Philips, SpectraWAVE, Svelte, Vascular Solutions
The planners and managers at Global Education Group have no relevant financial relationships to disclose.
The planners and managers at PlatformQ Health Education have no relevant financial relationships to disclose.
Instructions for Participation and Credit
In order to receive credit for this activity, the participant must (1) read the target audience, learning objectives, and disclosure statements, (2) complete the educational activity online, and (3) complete the post-test and activity evaluation. To receive AMA PRA Category 1 Credits™, participants must receive a minimum score of 70% on the post-test.
Hardware/Software Requirements
Participants will need a computer with a recent version of Adobe Flash installed, as well as an internet connection sufficient for streaming media.
Fee Information & Refund/Cancellation Policy
There is no fee for this educational activity
Disclosure of Unlabeled Use
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Global Education Group (Global) and PlatformQ Health Education, LLC do not recommend the use of any agent outside of the labeled indications.
The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Disclaimer
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed in this activity should not be used by clinicians without evaluation of patient conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.
Contact Information
Physician Accreditaiton Support
For information about the physician accreditation of this program, please contact Global at 303-395-1782 or [email protected].
Technical Support
For any technical issues or issues with your CME Certificate, please contact MedLive at 877-394-1306 or at [email protected].
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