Grant Support
This activity is supported by an independent medical educational grant from the REMS Program Companies (RPC).
Credits Available
- 1.5 AMA PRA Category 1 Credits™
1.5 AOA Category 1-B credits
All other health care professionals completing this course will be issued a statement of participation.
Target Audience
This activity is for osteopathic physicians and other health care professionals, including primary care/family medicine physicians, physician associates (PAs), nurse practitioners (NPs), and other specialties, including OB/GYN, nephrology, etc., who prescribe and/or participate in the treatment of patients taking mycophenolate products.
Program Overview
Prescribing mycophenolates comes with a responsibility that extends beyond the prescription pad. Despite clear risks, gaps in counseling and management continue to lead to preventable fetal exposure and harm. This activity will give you the tools to confidently navigate reproductive risk conversations, implement evidence-based pregnancy prevention strategies, and support informed patient decision-making. Participants will also learn how to clearly communicate teratogenic risks, select appropriate contraceptive approaches, and identify safer therapeutic alternatives when needed. You’ll also gain practical guidance on REMS requirements, including pregnancy reporting and engaging patients in the Mycophenolate Pregnancy Registry.
Learning Objectives
Upon completion of this activity, participants should be better able to:
- Recognize the increased risks of first trimester pregnancy loss and congenital malformations associated with mycophenolate use
- Explain the risks of mycophenolate exposure during pregnancy to patients
- Demonstrate effective patient education on pregnancy prevention, including appropriate contraceptive methods during treatment
- Identify alternative immunosuppressive therapies with lower embryofetal risk for use in pregnancy or preconception planning
- Describe the process for reporting pregnancies to the Mycophenolate Pregnancy Registry per REMS requirements
- Review approaches to encourage patient participation in the registry to contribute to safety monitoring and research
Faculty
Corinna Muller, DO, FACOOG (Distinguished), MBA
Medical Director, LifeMed Alaska
Obstetrics Transports and Medical Director, Perinatal Services at Providence Alaska
Medical Director, OB Hospitalist Group
Anchorage, AK
Emmie Strassberg, DO, FACOOG (Distinguished)
Maternal-Fetal Medicine Physician
OBTelecare
Summerville, SC
Accreditation Statement
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the American Osteopathic Association (AOA) and The France Foundation (TFF). The American College of Osteopathic Internists (ACOI) is accredited by the American Osteopathic Association to provide osteopathic continuing medical education for physicians.
Credit Designation
The American Osteopathic Association (AOA) designates this enduring material for a maximum of 1.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
The American College of Osteopathic Internists (ACOI) designates this activity for a maximum of 1.5 AOA Category 1-B credits and will report CME and specialty credits commensurate with the extent of the physician’s participation in this activity.
Disclosures of Conflict of Interest
The American Osteopathic Association has implemented a policy to comply with the current Accreditation Council for Continuing Medical Education (ACCME) Standards for Integrity and Independence in Accredited Continuing Education requiring mitigation of all conflicts of interest. Faculty declaring a relevant commercial interest must be identified in the activity syllabus and/or program.
In accordance with disclosure policies of AOA and ACCME, every effort has been made to ensure all CME activities are balanced, independent, objective, and scientifically rigorous. These policies include complying with ACCME’s Standards for Integrity and Independence in Accredited Continuing Education and mitigating all relevant conflicts of interest for all individuals in control of content.
The following faculty, presenters, and planning committee members have indicated that they have no relationship(s) that could be perceived as a potential conflict of interest:
Margaret Das, PhD
Medical content writer
No relevant financial disclosures
Heather Tarbox, MPH
TFF staff
No relevant financial disclosures
Emily Peck
TFF staff
No relevant financial disclosures
Heather Jastremski, MPH
AOA staff
No relevant financial disclosures
Darcy Steinberg
AOA staff
No relevant financial disclosures
Corinna Muller, DO
Steering committee member
No relevant financial disclosures
Emmie Strassberg, DO
Steering committee member
No relevant financial disclosures
Instructions for Participation and Credit
This is an online interactive case-based activity including an expert panel video series. There are no fees for participating in this CME activity. To participate in the activity, physicians will be required to take the following steps:
- Read the learning objectives and faculty disclosures
- Participate in the activity
- Complete the pretest, posttest, and activity evaluation
- Participants who successfully complete the evaluation and the posttest (scoring 70% or higher in a maximum of three attempts) will receive 1.5 AMA PRA Category 1 Credit(s)™ or 1.5 AOA Category 1-B credits
Course Viewing Requirements
Supported Browsers:
Internet Explorer 8.0+ for Windows 2003, Vista, XP, Windows 7, and Windows 8.1 and above
Google Chrome 28.0+ for Windows, Mac OS, or Linux
Mozilla Firefox 23.0+ for Windows, Mac OS, or Linux
Safari 6.0+ for Mac OSX 10.7 and above
Supported Phones & Tablets:
Android 4.0.3 and above
iPhone/iPad with iOS 6.1 or above
Disclaimer
The information in this educational activity is provided for general medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient's medical condition. The viewpoints expressed in this CME activity are those of the authors/faculty. They do not represent an endorsement by the AOA. In no event will the AOA be liable for any decision made or action taken in reliance upon the information provided through this CME activity.
Contact Information
For CME questions please contact: hjastremski@osteopathic.org