
Improving the Recognition, Diagnosis, and Treatment of Hereditary Transthyretin Amyloidosis
Released On
May 15, 2025
Expires On
May 15, 2026
Media Type
Internet
Completion Time
30 Minutes
Specialty
Cardiology, Genetics, Neurology, Ophthalmology, Pharmacy, Primary Care, Rheumatology
Topic(s)
Heart, Amyloidosis
Support was provided by an independent grant from Alnylam.
Credit Available
- Physicians — maximum of 0.5 AMA PRA Category 1 Credit™
All other healthcare professionals completing this course will be issued a statement of participation
Target Audience
This activity is designed to meet the educational needs of (MDs/DOs, NPs, PAs, nurses, pharmacists, geneticists) throughout the United States who are engaged in primary care or specialist care related to neurology, cardiology, or amyloidosis.
Program Overview
In this activity, Michelle Kaku, MD, provides a summary of ATTRv, its diagnosis, and currently available disease-modifying therapies, including the clinical evidence supporting their use, and recommendations for patient monitoring.
Learning Objectives
Upon completion of this activity, participants should be better able to:
- Summarize recent and emerging clinical research for the treatment of hereditary transthyretin (ATTRv) amyloidosis.
- Assess the impact of disease modifying therapies on patient burden of disease.
Faculty
Michelle Kaku, MD
Associate Professor of Neurology
Vice Chair for Education, Neurology Department
Icahn School of Medicine at Mount Sinai
New York, New York
Accreditation Statement

In support of improving patient care, Annenberg Center for Health Sciences at Eisenhower (Annenberg Center) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Credit Designation
The Annenberg Center designates this enduring material for a maximum of 0.5 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Disclosures of Conflicts of Interest
It is the policy of the Annenberg Center to ensure fair balance, independence, objectivity, and scientific rigor in all programming. All individuals with the potential to impact the content of an accredited education activity are expected to identify and reference off-label product use and disclose relevant financial relationships with ACCME-defined ineligible companies.
The Annenberg Center assesses relevant financial relationships with its instructors, planners, managers, and other individuals who are in a position to control the content of CE activities. All relevant financial relationships that are identified are mitigated by the Annenberg Center for fair balance, scientific objectivity of studies utilized in this activity, and patient care recommendations. The Annenberg Center is committed to providing its learners with high-quality CE activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of a commercial interest.
Faculty
- Michelle Kaku, MD
- Advisory Board: AstraZeneca, Intellia
Additional content planners
The following have no relevant financial relationships to disclose:
Jordan R Covvey, PharmD, PhD, BCPS (Medical Writer)
Annenberg Center for Health Sciences
All staff at the Annenberg Center have no relevant financial relationships to disclose.
All the relevant financial relationships listed for these individuals have been mitigated.
Instructions for Participation and Credit
This activity is an online enduring material. Successful completion is achieved by reading and/or viewing the materials, reflecting on its implications in your practice, and completing the assessment component.
Course Viewing Requirements
Supported Browsers:
Internet Explorer 8.0+ for Windows 2003, Vista, XP, Windows 7, Windows 8.1 and above
Google Chrome 28.0+ for Windows, Mac OS, or Linux
Mozilla Firefox 23.0+ for Windows, Mac OS, or Linux
Safari 6.0+ for Mac OSX 10.7 and above
Supported Phones & Tablets:
Android 4.0.3 and above
iPhone/iPad with iOS 6.1 or above
Disclosure of Unlabeled Use
The faculty for this activity has disclosed that there will be discussion about the use of products for non-FDA approved indications.
Disclaimer
Annenberg Center respects your privacy. We don’t share information you give us, or have the need to share this information in the normal course of providing the services and information you may request. If there should be a need or request to share this information, we will do so only with your explicit permission. See Privacy Statement and other information at https://annenberg.net/pages/privacyPolicy.php.
Contact Information
For CME questions please contact: [email protected].