Cognitive Impairment Associated With Schizophrenia: Evaluating Emerging Therapies
Released On
December 18, 2024
Expires On
December 18, 2025
Media Type
Internet
Completion Time
60 minutes
Specialty
Neurology, Primary Care, Psychiatry
Topics
Mental Health, Schizophrenia
Provider Statement
This activity is provided by Integrity CE, LLC.
Disclosure of Commercial Support
This activity is supported by an independent medical education grant from Boehringer Ingelheim Pharmaceuticals, Inc.
Credit Available
- Physicians - maximum of 1.0 AMA PRA Category 1 Credit™
All other healthcare professionals completing this course will be issued a statement of participation.
Target Audience
This educational activity has been designed to meet the needs of psychiatrists, psychiatry mental health therapists (eg, psychologists, social workers, case managers), nurse practitioners, physician assistants, pharmacists, primary care providers, and other clinicians involved in the management of patients with cognitive impairment associated with schizophrenia (CIAS).
Program Overview
CIAS is a core symptom domain of schizophrenia that can impose even greater long-term damage than the delusions and hallucinations this psychiatric disorder is known for. CIAS, which is marked by impairments in neurocognition and social cognition, can start in early childhood — long before any signs of psychosis. For many patients, functional outcomes are so compromised that performing activities of daily life and living independently are impossible. One therapy in late-phase development is showing promise for CIAS as an add-on treatment to standard-of-care antipsychotics.
Learning Objectives
Upon completion of this educational activity, participants should be able to:
- Characterize the disease burden and unmet treatment needs of patients with CIAS
- Explain what is known about the pathophysiology of CIAS and how its symptoms differ from those in the negative domain
- Select a therapeutic agent for patients affected by CIAS based on safety, efficacy, and mechanism of action
Faculty
John H. Krystal, MD
Robert L. McNeil, Jr. Professor of Translational Research
Chair, Yale Department of Psychiatry
Chief of Psychiatry, Yale-New Haven Hospital
Co-Director, Yale Center for Clinical Investigation
New Haven, Connecticut
Stephen R. Marder, MD
Distinguished Professor of Psychiatry
Semel Institute for Neuroscience at UCLA
Director, VA Desert Pacific Mental Illness Research, Education, and Clinical Center
Los Angeles, California
Accreditation Statement
Integrity CE, LLC is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Credit Designation
Integrity CE, LLC designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Disclosures of Conflicts Of Interest
Integrity CE, LLC requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any financial relationships with ineligible companies. All identified relevant financial relationships are thoroughly vetted by Integrity CE, LLC for fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations. All relevant financial relationships have been mitigated.
The following faculty/planners reported the financial relationships or relationships to products or devices they have with ineligible companies related to the content of these CME activities:
John H. Krystal, MD
Consultation: AbbVie, Inc, Biogen, Idec, MA, Bionomics, Limited (Australia), BioXcel Therapeutics, Boehringer Ingelheim International, Cerevel Therapeutics, LLC, Clearmind Medicine, Inc., Cybin IRL, EpiVario, Inc., Janssen Pharmaceutical, Jazz Pharmaceuticals, Inc., Leal Therapeutics, Inc., Manifest Technologies, MycoMedica Life Sciences, PBC, Neurocrine Biosciences, Inc., Novartis Pharmaceuticals, Otsuka America Pharmaceutical, Inc., Praxis Precision Medicines, Inc., Psylo PTY LTD., Response Pharmaceuticals, Inc., Reunion Neuroscience, Spring Care, Inc., Takeda Pharmaceuticals, International, Terran Biosciences, Inc., Tetricus, Inc., WebMD/Medscape, LLC
Scientific Advisory Board: Biogen, Idec, MA, Biohaven Pharmaceuticals, BioXcel Therapeutics, Inc. (Clinical Advisory Board), Cerevel Therapeutics, LLC, Certigo Therapeutics, Inc, Clearmind Medicine, Inc., Coalition for Aligning Science, Delix Therapeutics, Inc., EpiVario, Inc., Freedom Biosciences, Inc., Mindset Admin, LLC (DBA Being Health), MycoMedica Life Sciences, PBC (PMDD Advisory Board), Neumora Therapeutics, Inc., Neurocrine Biosciences, Inc., Novartis Pharmaceuticals Corporation, Praxis Precision Medicines, Inc., PsychoGenics, Inc., Response Pharmaceuticals, Inc., ReST Therapeutics, Takeda Industries, Terran Biosciences, Inc., Tetricus, Inc.
Stock: Biohaven Pharmaceuticals, Spring Care, Inc.
Stock Options: Biohaven Pharmaceuticals Medical Sciences, Clearmind Medicine, Inc., Delix Therapeutics, Inc., EpiVario, Inc., Manifest Technologies, Neumora Therapeutics, Inc., Psylo PTY LTD., ReST Therapeutics, Spring Care, Tempero Bio, Inc., Terran Biosciences, Inc., Tetricus, Inc.
Steven R. Marder, MD
Consultation: Boehringer Ingelheim, Karuna, Merck, Newron, Sunovion
Research: Boehringer Ingelheim
The Integrity CE, LLC planners and managers do not have any financial relationships or relationships to products or devices with ineligible companies.
Instructions for Participation and Credit
There are no fees for participating and receiving CME credit for this activity. During the period of December 18, 2024 through December 18, 2025, participants must:
- Read the learning objectives
- Complete the pretest
- Study the educational activity
- Complete the posttest and the evaluation form
A statement of credit will be issued only upon receipt of a completed posttest with a score of 60% or better and a completed activity evaluation form.
Course Viewing Requirements
Supported Browsers:
Internet Explorer 8.0+ for Windows 2003, Vista, XP, Windows 7, Windows 8.1 and above
Google Chrome 28.0+ for Windows, Mac OS, or Linux
Mozilla Firefox 23.0+ for Windows, Mac OS, or Linux
Safari 6.0+ for Mac OSX 10.7 and above
Supported Phones & Tablets:
Android 4.0.3 and above
iPhone/iPad with iOS 6.1 or above
Disclosure of Unlabeled Use
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Integrity CE, LLC does not recommend the use of any agent outside of the labeled indications.
The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Disclaimer
The information provided at this activity is for continuing education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient’s medical condition.
Contact Information
For information about ACCME accreditation of this activity, please contact Integrity CE, LLC at (855) 835-4004 or [email protected].