Taking the Kidneys to Heart: Managing CKD-Related Anemia With Emerging HIF-PHIs
Released On
December 16, 2022
Expires On
December 16, 2023
Media Type
Internet
Completion Time
60 minutes
Specialty
Cardiology
Topic(s)
Cardiovascular Disease, Nephrology
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This CME activity for ACCME credit is provided by Integrity Continuing Education, Inc.
This CE activity for ANCC and ACPE credit is jointly provided by Global Education Group and Integrity Continuing Education, Inc.


This educational activity is supported by an educational grant from GlaxoSmithKline.
Credit Available
- Physicians — maximum of 1.0 AMA PRA Category 1 Credit™/1.0 MOC Point
- Nurses — maximum 1.0 ANCC contact hour
- Pharmacists — maximum 1.0 ACPE contact hour
All other healthcare professionals completing this course will be issued a statement of participation.
Target Audience
This educational program is designed for hospitalists, general internists, subspecialists, and family practitioners caring for hospitalized patients.
Program Overview
Anemia is a common disease sequela of chronic kidney disease (CKD) that worsens and complicates the bidirectional disease continuum between the kidneys and heart. Anemia in CKD can be treated, which can extend the lives of CKD patients as well as reduce hospitalizations and improve quality of life, yet it is persistently undermanaged because current treatments are in and of themselves linked with increased risk for major cardiovascular events. They are also injectable or intravenous and definitely invasive, which no doubt limits patient acceptance.
Hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) are a novel class of small-molecule oral drugs in late-phase development and under review by the FDA that are poised to potentially change the treatment paradigm for patients with CKD-related anemia. Join our esteemed faculty for a review of current and emerging treatments, as if or when new therapies are approved, physicians and other clinicians who manage patients with anemia in CKD will need to be familiar with these novel agents and the clinical trial data that support their use in appropriately selected patients.
Learning Objectives
Upon completion of this activity, participants should be able to:
- Clarify the disease burden imposed by untreated or undertreated anemia in patients with CKD, including in racially diverse patients
- Correlate the pathophysiology of anemia in CKD with viable therapeutic targets
- Identify appropriate candidates for emerging CKD-related anemia treatments among patients on or not on dialysis based on efficacy and safety data from recent clinical trials
Faculty

Biff F. Palmer, MD, FACP, FASN
Professor of Internal Medicine
University of Texas Southwestern Medical Center
Dallas, Texas
Physician Accreditation Statement
Integrity Continuing Education, Inc. is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Physician Credit Designation
Integrity Continuing Education, Inc. designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.0 MOC point in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.
Nursing Continuing Education
Global Education Group is accredited with distinction as a provider of nursing continuing professional development by the American Nurses Credentialing Center’s Commission on Accreditation.
This educational activity for 1.0 contact hour is provided by Global Education Group. Nurses should claim only the credit commensurate with the extent of their participation in the activity.
Pharmacist Continuing Education
Accreditation Statement
Global Education Group is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education with Commendation.
Credit Designation
Global Education Group designates this continuing education activity for 1.0 contact hour (0.1 CEU) of the Accreditation Council for Pharmacy Education. (Universal Activity Number - 0530-9999-22-240-H01-P.)
This is a knowledge-based activity.
Fee Information
There is no fee for completing this program.
Disclosures of Conflicts of Interest
Integrity Continuing Education, Inc. and Global Education Group adhere to the policies and guidelines, including the Standards for Integrity and Independence in Accredited CE, set forth to providers by the Accreditation Council for Continuing Medical Education (ACCME) and all other professional organizations, as applicable, stating those activities where continuing education credits are awarded must be balanced, independent, objective, and scientifically rigorous. All persons in a position to control the content of an accredited continuing education program provided by Integrity Continuing Education, Inc. and Global Education Group are required to disclose all financial relationships with any ineligible company within the past 24 months. All financial relationships reported are identified as relevant and mitigated by Integrity Continuing Education, Inc. and Global Education Group in accordance with the Standards for Integrity and Independence in Accredited CE in advance of delivery of the activity to learners. The content of this activity was vetted by Integrity Continuing Education, Inc. and Global Education Group to assure objectivity and that the activity is free of commercial bias.
All relevant financial relationships have been mitigated.
The following faculty/planners reported the financial relationships or relationships to products or devices they have with ineligible companies related to the content of these CE/CME activities:
Biff F. Palmer, MD has no real or apparent conflicts of interest to disclose.
The planners and managers at Integrity Continuing Education, Inc. and Global Education Group have no relevant financial relationships to disclose.
Instructions for Participation and Credit
There are no fees for participating and receiving CE/CME credit for this activity. During the period of December 16, 2022 through December 16, 2023 participants must:
- Complete the pretest.
- View the material.
- Complete the posttest and the evaluation form
A statement of credit will be issued only upon receipt of a completed activity evaluation form and a completed posttest with a score of 100%. For pharmacist/ACPE learners, please check the CPE monitor for your CE credit within 60 days of the activity. Credit cannot be issued after 60 days.
Course Viewing Requirements
Supported Browsers:
Internet Explorer 8.0+ for Windows 2003, Vista, XP, Windows 7, Windows 8.1 and above
Google Chrome 28.0+ for Windows, Mac OS, or Linux
Mozilla Firefox 23.0+ for Windows, Mac OS, or Linux
Safari 6.0+ for Mac OSX 10.7 and above
Supported Phones & Tablets:
Android 4.0.3 and above
iPhone/iPad with iOS 6.1 or above
Disclosure of Unlabeled Use
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Integrity Continuing Education, Inc. and Global Education Group do not recommend the use of any agent outside of the labeled indications.
The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Disclaimer
The information provided at this activity is for continuing education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient’s medical condition.
Contact Information
For information about ACCME accreditation of this activity, please contact Integrity Continuing Education, Inc. at (855) 835-4004 or cme@integrityce.com.
For information about ACPE or ANCC accreditation of this activity, please contact Global Education Group at (303) 395-1782 or cme@globaleducationgroup.com.