
Expert Illustrations & Commentaries™: Targeting the Complement System to Optimize Treatment of Cold Agglutinin Disease
Released On
February 28, 2023
Expires On
February 28, 2024
Media Type
Internet
Completion Time
60 minutes
Specialty
Hematology/Oncology
Topic(s)
Bleeding Disorders, Hemophilia
This activity is provided by Physicians’ Education Resource®, LLC.

This activity is supported by an educational grant from Sanofi.
Credit Available
- Physicians — maximum of 1.0 AMA PRA Category 1 Credit(s)™
- Nurses — 1.0 Contact Hours
All other healthcare professionals completing this course will be issued a statement of participation.
Target Audience
This educational activity is directed toward hematologists. Nurses, nurse practitioners, physician assistants, and other clinicians involved in the management of patients with cold agglutinin disease are invited to attend.
Activity Overview
This Expert Illustrations and Commentaries™ is a video-based program in which 2 experts discuss strategies for the management of cold agglutinin disease (CAD). In this activity, the faculty focus on the role of the complement system in the pathophysiology of cold agglutinin disease and ways that current and emerging therapies target the pathophysiologic processes at play. The faculty discussion is enriched with the use of video animations to illustrate the complement pathway, as well as the mechanism of action of current and emerging complement-directed therapies. The use of animated segments helps make somewhat complicated subject matter more easily understood. This unique format is designed to help clinicians identify best practices in the treatment of patients with CAD.
Learning Objectives
Upon successful completion of this activity, you should be better prepared to:
- Outline the role of the complement pathway in the pathogenesis of CAD
- Implement diagnostic algorithms to accurately identify patients with CAD
- Assess clinical trial data for current and emerging agents used to treat patients with CAD
Faculty

Jeremy Lorber, MD
Assistant Professor
Department of Medicine
Cedars-Sinai
Los Angeles, CA

Ilene Ceil Weitz, MD
Professor of Medicine
Jane Anne Nohl Division of Hematology
Keck School of Medicine - University of Southern California
Los Angeles, CA
Accreditation/Credit Designation
Physicians’ Education Resource®, LLC, is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Physicians’ Education Resource®, LLC, designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Physicians’ Education Resource®, LLC is approved by the California Board of Registered Nursing, Provider #16669, for 1.0 Contact Hours.
Disclosures of Conflicts of Interest
The staff of Physicians’ Education Resource®, LLC have no relevant financial relationships with ineligible entities.
- Jeremy Lorber, MD
- Speakers’ Bureau: Sanofi
Ilene Ceil Weitz, MD, has no relevant financial relationships with ineligible companies.
PER® mitigated all COI for faculty, staff, and planners prior to the start of this activity by using a multistep process.
Course Viewing Requirements
Supported Browsers:
Internet Explorer 8.0+ for Windows 2003, Vista, XP, Windows 7, Windows 8.1 and above
Google Chrome 28.0+ for Windows, Mac OS, or Linux
Mozilla Firefox 23.0+ for Windows, Mac OS, or Linux
Safari 6.0+ for Mac OSX 10.7 and above
Supported Phones & Tablets:
Android 4.0.3 and above
iPhone/iPad with iOS 6.1 or above
Off-Label Disclosure and Disclaimer
This activity may or may not discuss investigational, unapproved, or off-label use of drugs. Learners are advised to consult prescribing information for any products discussed. The information provided in this accredited activity is for continuing education purposes only and is not meant to substitute for the independent clinical judgment of a healthcare professional relative to diagnostic, treatment, or management options for a specific patient’s medical condition. The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of PER® or any company that provided commercial support for this activity.