.jpg)
Catching Zzzs: The Role of Dual Orexin Receptor Antagonists for Insomnia
Released On
February 15, 2023
Expires On
February 15, 2024
Media Type
Internet
Completion Time
30 minutes
Specialty
Education, Neurology, Other, Pharmacy, Primary Care, Psychiatry, Sleep Medicine
Topic(s)
Insomnia, Sleep Medicine
Scroll to the Bottom of this Information to Begin this Course
This activity is jointly provided by Global Education Group and Spire Learning.
This activity is supported by an independent educational grant from Eisai.
Credit Available
- Physicians — maximum of 0.5 AMA PRA Category 1 Credit(s)™
All other health care professionals completing this course will be issued a statement of participation.
Target Audience
This activity has been designed to meet the educational needs of physicians, nurse practitioners, physician assistants, and pharmacists practicing in primary care, neurology, and psychiatry.
Program Overview
Insomnia is responsible for a wide range of short-term and long-term impairments and negative health outcomes. Differences in mechanisms among insomnia therapies have important implications for their use in specific patients and among specific patient populations. Dual orexin receptor antagonists (DORAs) are a relatively new option for the treatment of insomnia. In this 30-minute educational podcast, expert Phyllis Zee, MD, offers valuable insights into the disease burdens that affect patients with insomnia, mechanism of action of DORAs in contrast to other insomnia agents, clinical trial data for DORAs in the setting of insomnia, and patient scenarios where DORAs may be considered.
Learning Objectives
Upon completion of this activity, participants should be better able to:
- DESCRIBE the disease burdens that affect patients with insomnia
- DIFFERENTIATE the mechanism of action of DORAs in contrast to the mechanisms of other insomnia agents
- EVALUATE clinical trial data for DORAs approved for insomnia
- IDENTIFY evidence-based guidance to determine patient scenarios where DORAs may be considered for insomnia
- Agenda (30-Minute Podcast)
-
- Prevalence and Disease Burdens of Insomnia
- Available Insomnia Therapies: Mechanisms of Action of DORAs, BZDs, and BzRAs
- DORAs: Evidence-Based Use in Clinical Practice
- Key Takeaway Messages/Conclusion
Faculty
Phyllis C. Zee, MD, PhD
Director, Center for Circadian and Sleep Medicine
Chief of Sleep Medicine in the Department of Neurology
Benjamin and Virginia T. Boshes Professor of Neurology
Professor of Neurology (Sleep Medicine)
Northwestern University Feinberg School of Medicine
Chicago, IL
Phyllis C. Zee, MD, PhD, is the Benjamin and Virginia T. Boshes Professor in Neurology and Professor of Neurobiology at Northwestern University. She is also the Director of the Center for Circadian and Sleep Medicine (CCSM) and Chief of the Division of Sleep Medicine at Northwestern University’s Feinberg School of Medicine. As Director of CCSM, Dr Zee oversees an interdisciplinary program in basic and translational sleep and circadian rhythm research, and findings from her team have paved the way for innovative approaches to improve sleep and circadian health. Dr Zee practices sleep medicine at Northwestern Medicine’s Center for Circadian and Sleep Medicine in downtown Chicago and is the founder of the first circadian medicine clinic in the US, where innovative treatments are available for patients with circadian rhythm disorders.
Dr Zee has authored more than 300 peer-reviewed original articles, reviews, and book chapters on the topics of sleep, circadian rhythms, and sleep/wake disorders. She has also trained more than 50 predoctoral and postdoctoral students and has mentored numerous faculty members. Dr Zee is a fellow of the American Academy of Sleep Medicine, a member of the American Academy of Neurology, and a member of the American Neurological Association. She has served on numerous national and international committees, National Institutes of Health (NIH) scientific review panels, and international advisory boards. She is past President of the Sleep Research Society, past President of the Sleep Research Foundation, past Chair of the NIH Sleep Disorders Research Advisory Board, a past member of the NIH National Heart Lung and Blood Disorders Advisory Council, and the current President of the World Sleep Society. Dr Zee is the recipient of the 2011 American Academy of Neurology Sleep Science Award, 2014 American Academy of Sleep Medicine academic honor, William C. Dement Academic Achievement Award, 2020 Sleep Research Society Distinguished Scientist Award (the society’s highest award, which recognizes significant, original, and sustained scientific contributions), and the 2021 National Sleep Foundation Lifetime Achievement Award.
Physician Accreditation Statement
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Global Education Group (Global) and Spire Learning. Global is accredited by the ACCME to provide continuing medical education for physicians.
Physician Credit Designation
Global Education Group designates this enduring activity for a maximum of 0.5 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Disclosures of Relevant Financial Relationships
Global Education Group (Global) adheres to the policies and guidelines, including the Standards for Integrity and Independence in Accredited CE, set forth to providers by the Accreditation Council for Continuing Medical Education (ACCME) and all other professional organizations, as applicable, stating those activities where continuing education credits are awarded must be balanced, independent, objective, and scientifically rigorous. All persons in a position to control the content of an accredited continuing education program provided by Global are required to disclose all financial relationships with any ineligible company within the past 24 months to Global. All financial relationships reported are identified as relevant and mitigated by Global in accordance with the Standards for Integrity and Independence in Accredited CE in advance of delivery of the activity to learners. The content of this activity was vetted by Global to assure objectivity and that the activity is free of commercial bias.
All relevant financial relationships have been mitigated.
FACULTY
Phyllis C. Zee, MD, PhD
- Disclosures:
-
- Consultant: CVS Caremark; Eisai Inc.; Idorsia Pharmaceuticals Ltd; Jazz Pharmaceuticals, Inc.; Sleep Number Corporation
- Contracted Research: Vanda Pharmaceuticals
- Honoraria: CVS Caremark; Eisai Inc.; Idorsia Pharmaceuticals Ltd; Jazz Pharmaceuticals, Inc.; Sleep Number Corporation
- Stock Shareholder: Teva Pharmaceutical Industries Ltd.
EDUCATIONAL PLANNING COMMITTEE
Global Education Group
The planners and managers at Global Education Group have no relevant financial relationships to disclose.
Spire Learning
Mairead Early (Senior Program Manager), Ashton Webb, PharmD, BCACP (Clinical Director), and Allison Goldberg, MPA (Senior Director, Grants and Education): No relevant financial relationships with any commercial interests.
Instructions for Participation and Credit
There are no fees for participating and receiving CME credit for this activity. To receive CME credit participants must:
- Read the objectives, disclosures, and other introductory CME information
- Complete the preassessment prior to the start of the activity
- Participate in the Insomnia activity
- Submit the postassessment and evaluation at the conclusion of the activity
- Receive a passing score of at least 70% on the postassessment
- Certificates will be emailed to the participant
If you are seeking credit, you must complete the evaluation at the conclusion of the activity.
Course Viewing Requirements
Supported Browsers:
Internet Explorer 8.0+ for Windows 2003, Vista, XP, Windows 7, Windows 8.1 and above
Google Chrome 28.0+ for Windows, Mac OS, or Linux
Mozilla Firefox 23.0+ for Windows, Mac OS, or Linux
Safari 6.0+ for Mac OSX 10.7 and above
Supported Phones & Tablets:
Android 4.0.3 and above
iPhone/iPad with iOS 6.1 or above
Disclosure of Unlabeled Use
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Global Education Group (Global) and Spire Learning do not recommend the use of any agent outside of the labeled indications. The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Disclaimer
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed in this activity should not be used by clinicians without evaluation of patient conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.
Privacy Policy
Spire Learning, LLC is committed to protecting the privacy of personal information from our participants and educational collaborators. Spire maintains physical, electronic, and procedural safeguards that comply with federal regulations to protect against the loss, misuse, or alteration of personal information.
Collection and use of your personal information
The submission of certain personally identifiable information is necessary to award and track the credits participants may earn after completing an activity. Required items include first name, last name, degree, and email address. These items are necessary. Participants are also required to complete an evaluation of each activity. All evaluative information submitted is collected and retained, and used by Spire Learning, LLC to continuously improve the learning experience.
Spire Learning, LLC will not transfer, sell, or share personal information with outside parties or otherwise disclose personal information unless required to in a legal process. Spire will retain your personal data only for the period necessary to accomplish the stated purposes and to comply with applicable laws.
Copyright Information
Copyright © 2023 by Spire Learning, LLC and Global Education Group. All rights reserved including translation into other languages. No part of this publication or activity may be reproduced or transmitted in any form, by any means, without prior written permission of Spire Learning, LLC.
Contact Information
For information about the accreditation of this program, please contact Global at 303-395-1782 or cme@globaleducationgroup.com.