
Acute Graft Versus Host Disease: A Clinical Compendium on Answers to Clinicians’ Questions in Prevention and Management
Released On
March 27, 2023
Expires On
March 27, 2024
Media Type
Internet
Completion Time
60 minutes
Specialty
Dermatology, Hematology-Oncology, Neurology, Pathology, Surgery
Topic(s)
Leukemia, Lymphoma, Oncology, Surgery
This activity is provided by Annenberg Center for Health Sciences at Eisenhower.

This activity is supported by an educational grant from CSL Behring.
Credit Available
- Physicians — maximum of 1.0 AMA PRA Category 1 Credit(s)™
- Nurses — 1.0 Contact Hours (including 0.5 pharmacology hours)
All other healthcare professionals completing this course will be issued a statement of participation.
Target Audience
This activity was developed for hematologists, oncologists, physician associates, nurse practitioners, nurses and all other healthcare professionals involved in the care of patients with graft versus host disease.
Program Overview
Bone marrow transplant specialist Nelson Chao, MD, dives into the topic of acute graft-versus-host disease (aGVHD), the most common complication after hematopoietic stem cell transplant (HSCT). Discussion surrounds the classification, diagnosis, severity, grading, and staging of aGVHD. He discusses recent guideline updates and recommended clinical management strategies for the prevention and treatment of patients with aGVHD and provides his insight into the current and emerging therapies undergoing evaluation in late-phase clinical trials. Finally, Dr. Chao highlights the burden of disease for patients, identifies patient resources and supportive measures, and provides his clinical perspective on the future management of patients with aGVHD.
Learning Objectives
Upon completion of this activity, participants should be better able to:
- Classify the severity of acute graft-versus-host disease (aGVHD) according to recent grading and staging guidelines.
- Outline the pharmacologic therapies to treat aGVHD, including guideline recommendations for their use when available.
- Use best practice strategies for prevention and treatment of newly diagnosed aGVHD.
Faculty

Nelson Chao, MD, MBA
Donald D. and Elizabeth G. Cooke Professor
Chief, Division of Hematologic Malignancies and Cellular Therapy/BMT
Director, Global Cancer
Duke University
Durham, North Carolina
Accreditation Statement
In support of improving patient care, Annenberg Center for Health Sciences at Eisenhower (Annenberg Center) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Physician Credit Designation
The Annenberg Center designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Nursing Continuing Education
Annenberg Center for Health Sciences at Eisenhower designates this enduring activity for a maximum of 1.0 ANCC contact hour, including 0.5 pharmacology hour.
Provider is approved by the California Board of Registered Nursing, Provider #13664, for 1.0 contact hour. To receive credit for education contact hours outside of the state of California, please check with your state board of registered nursing for reciprocity.
Disclosures of Conflicts of Interest
Nelson Chao, MD, MBA, has no relevant financial relationship to disclose.
The faculty for this activity has disclosed that there will be no discussion about the use of products for non-FDA approved applications.
Additional content planners
The following have no relevant financial relationship to disclose:
Kam Newman, MD (Peer Reviewer)
Madison Saxton, PharmD, BCOP (Medical Writer)
Amber Lambert, DNP (Nurse Planner)
Annenberg Center for Health Sciences
All staff at the Annenberg Center have no relevant financial relationships to disclose.
All the relevant financial relationships listed for these individuals have been mitigated.
Instructions for Participation and Credit
This activity is an online enduring material. Successful completion is achieved by reading and/or viewing the materials, reflecting on its implications in your practice, and completing the assessment component.
Course Viewing Requirements
Supported Browsers:
Internet Explorer 8.0+ for Windows 2003, Vista, XP, Windows 7, Windows 8.1 and above
Google Chrome 28.0+ for Windows, Mac OS, or Linux
Mozilla Firefox 23.0+ for Windows, Mac OS, or Linux
Safari 6.0+ for Mac OSX 10.7 and above
Supported Phones & Tablets:
Android 4.0.3 and above
iPhone/iPad with iOS 6.1 or above
Disclosure of Unlabeled Use
The faculty for this activity has disclosed that there will be no discussion about the use of products for non-FDA approved applications.
Disclaimer
The ideas and opinions presented in this educational activity are those of the faculty and do not necessarily reflect the views of the Annenberg Center and/or its agents. As in all educational activities, we encourage practitioners to use their own judgment in treating and addressing the needs of each individual patient, taking into account that patient's unique clinical situation. The Annenberg Center for Health Sciences at Eisenhower disclaims all liability and cannot be held responsible for any problems that may arise from participating in this activity or following treatment recommendations presented.
Contact Information
For CME questions please contact: ce@annenberg.net.