Jointly sponsored/co-provided by Postgraduate Institute for Medicine and CE Health Interactive.
This activity is supported in part by independent education grants from Bristol-Myers Squibb and AztraZeneca.
Release date: January 15, 2014
Valid through: January 31, 2015
This activity has been designed to meet the educational needs of endocrinologists, nephrologists, physicians, diabetes educators, nurse practitioners, registered nurses, and other healthcare providers involved in the management of patients with type 2 diabetes.
Traditional discussions of the pathogenesis of hyperglycemia and glucose regulation tend to focus on the intestine, pancreas, liver, adipose tissue, and muscle. However, more recent findings have confirmed the role of the kidney as a major organ involved in the regulation of glucose homeostasis under both physiologic and pathologic conditions. Regulation of glucose by the kidneys includes the release of glucose into circulation via gluconeogenesis, glucose uptake, and glucose reabsorption. These findings have enhanced our understanding of the processes that comprise glucose reabsorption and release, including the function of renal sodium-glucose linked transporters (SGLTs) and facilitated glucose transporters (GLUTs) in glucose reabsorption, and have led to new perceptions of the pathophysiologic disorders that may contribute to the development of hyperglycemia and type 2 diabetes. This activity will provide insight into the kidneys' role in normal human physiology, an overview of its anatomical structure and function, the potential impact of glucose imbalance on the kidneys, and a mechanistic review of how the inhibition of these genes contributes to glucose regulation.
All other healthcare professionals completing this course will be issued a statement of participation.