Sparing and Restoring the Gut Microbiota:
A Collaborative Approach to Treating and Preventing Recurrent C. difficile Infection
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Recurrent episodes of C. difficile continue to pose a significant burden on patients, clinicians, and the healthcare system. The management of recurrent and refractory C. difficile is complex and challenging. These activities review the role of the gut microbiome in C. difficile infection, discuss evidence-based guidelines for treatment and prevention of recurrent infection, and describe emerging restoration approaches that reduce complications and improve clinical outcomes.